Related Experiment Videos
Detecting airflow obstruction in smoking cessation trials: a rationale for routine spirometry
Abraham Bohadana1, Fredrik Nilsson, Yves Martinet
1INSERM, ESPRI EP2R, Faculté de Médecine, B.P. 184 - 9, Av de la Forêt de Haye, 54505 Vandoeuvre-lès-Nancy, France. bohadana@u420.nancy.inserm.fr
Chest
|September 16, 2005
Summary
Spirometry screening in smoking cessation trials reveals significant airflow obstruction. Many participants with this condition miss follow-up, remaining unaware of their lung health risks.
Area of Science:
- Pulmonary Medicine
- Clinical Trials
- Public Health
Background:
- Spirometry is underutilized in smoking cessation research.
- Smokers with undiagnosed airflow obstruction risk accelerated lung function decline.
- Lack of follow-up for these individuals exacerbates health risks.
Purpose of the Study:
- To determine the prevalence of airflow obstruction in smokers undergoing cessation trials.
- To assess the rate of lost-to-follow-up among smokers with airflow obstruction.
Main Methods:
- 598 smokers in two trials underwent spirometry at baseline and 1 year.
- Participants received nicotine replacement therapy.
- Smoking status was categorized as quitters, reducers, or continuing smokers.
Main Results:
- 17.6% of participants had airflow obstruction at enrollment.
- Of those with obstruction, 69.3% were mild, 22.7% moderate, and 8% severe.
- 75 subjects with obstruction were lost to follow-up.
Conclusions:
- Spirometry effectively identifies airflow obstruction in smoking cessation trial participants.
- A high proportion of subjects with obstruction were lost to follow-up, unaware of their condition.
- Identifying and referring smokers with airflow obstruction for further care is crucial.