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Related Experiment Videos

Echocardiographic abnormalities in ankylosing spondylitis.

T W O'Neill1, G King, I M Graham

  • 1Department of Rheumatology, St Vincents Hospital, Dublin, Ireland.

Annals of the Rheumatic Diseases
|May 1, 1992
PubMed
Summary

Ankylosing spondylitis patients show significant cardiac issues, including aortic incompetence, detected early by Doppler echocardiography. This highlights the need for cardiac screening in long-term ankylosing spondylitis (AS) management.

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Area of Science:

  • Cardiology
  • Rheumatology
  • Medical Imaging

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the axial skeleton.
  • Cardiac involvement in AS, particularly aortic valve disease, can be a serious complication.
  • Early detection of cardiac abnormalities is crucial for managing AS patients.

Purpose of the Study:

  • To assess the prevalence of cardiac disease in patients with long-standing ankylosing spondylitis.
  • To investigate the utility of Doppler echocardiography in detecting subclinical cardiac abnormalities in AS.
  • To identify clinical factors associated with cardiac involvement in AS.

Main Methods:

  • Twenty-four patients with AS (disease duration ≥10 years) underwent cardiac assessment.

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  • Cardiac evaluation included clinical examination, electrocardiography, and Doppler echocardiography.
  • A control group matched for age and sex was used for comparison.

    • Main Results:

    • Seven patients (29%) exhibited evidence of cardiac disease.
    • Findings included pericardial effusion, conduction abnormalities, and aortic incompetence.
    • Doppler echocardiography detected clinically silent aortic incompetence and a novel finding of posterior aortic wall thickening in one AS patient.
    • Patients with cardiac abnormalities were older, had longer disease duration, and more peripheral joint disease.

    Conclusions:

    • Cardiac disease is prevalent in patients with long-term ankylosing spondylitis.
    • Doppler echocardiography is effective in identifying early-stage cardiac involvement, including subclinical aortic valve disease.
    • Age, disease duration, and peripheral joint involvement may be associated with increased cardiac risk in AS.