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Tuberculosis associated with gastrectomy
Toshinobu Yokoyama1, Rumi Sato, Toru Rikimaru
1First Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan. tyokoyama@cogeco.ca
Summary
Gastric resection may increase tuberculosis risk, particularly reactivation in elderly patients with poor nutrition. This study highlights gastrectomy as a potential risk factor for tuberculosis development and recurrence.
Area of Science:
- Medicine
- Public Health
Background:
- Gastric resection is common in Japan for conditions like gastric cancer and ulcers.
- Elderly populations often have a history of both gastrectomy and tuberculosis.
Purpose of the Study:
- To investigate the incidence and clinical features of tuberculosis in patients who have undergone gastric resection.
- To identify potential risk factors for tuberculosis development or reactivation post-gastrectomy.
Main Methods:
- Retrospective study of 26 patients with tuberculosis and a history of gastric resection.
- Analysis of patient demographics, body mass index (BMI), and glucose tolerance.
- Examination of tuberculosis prevalence trends over a three-year period.
Main Results:
- The prevalence of gastrectomy among tuberculosis patients showed an average 3-year incidence of 9.1%.
- A significant proportion of patients (9 out of 21) had a BMI below 18 kg/m2, indicating poor nutrition.
- Impaired glucose tolerance, including oxyhyperglycemia or diabetes mellitus, was identified as a risk factor.
Conclusions:
- Gastric resection may be a significant risk factor for tuberculosis reactivation, especially in malnourished individuals.
- Poor nutritional status post-gastrectomy is a key indicator for tuberculosis risk.
- Further research is warranted to understand the link between gastrectomy and tuberculosis pathogenesis.