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In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration
Published on: February 23, 2019
Porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease: case report
I-Shu Chen1, Hung-Wen Kuo, Hock-Liew Eng
1Department of Dermatology, Veterans General Hospital, Kaohsiung, Taiwan. chenishu@sina.com.tw
Background:
Chronic arsenism with Bowen's disease is often seen in patients who drink water containing a high level of arsenic. Inorganic arsenic has demonstrated an increased risk of skin cancer.
Objective:
We present a rare case of porocarcinoma in a patient with chronic arsenism and multiple Bowen's disease.
Methods:
Report of a case and review of the literature.
Results:
A case of porocarcinoma arising in a patient with chronic arsenism is presented. The tumor was completely excised by means of wide excision with a 5 mm free margin. The surgical defect was reconstructed with a rhombic flap.
Conclusion:
Chronic arsenism can induce various skin neoplasms, possibly including porocarcinoma.
