Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biopsy type does not influence sentinel lymph node status.

Anees B Chagpar1, Charles R Scoggins, Sunati Sahoo

  • 1Department of Surgery, University of Louisville, 315 E. Broadway, Suite 312, Louisville, KY 40202, USA. anees.chagpar@nortonhealthcare.org

American Journal of Surgery
|September 17, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defining textbook outcome for distal pancreatectomy by systematic review. Is it clinically relevant?

Surgery·2026
Same author

Evaluating adherence to literature-derived systemic therapy standards for resectable intrahepatic cholangiocarcinoma: A systematic review and cohort study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Positron emission tomography-guided radiation therapy: An overview of the RefleXion SCINTIX biology-guided platform.

Journal of radiosurgery and SBRT·2026
Same author

Defining Stereotactic Body Radiation Therapy: A (Hi)story of Precision and Accuracy.

International journal of radiation oncology, biology, physics·2026
Same author

Commissioning of the RefleXion X1 Linear Accelerator and Development of a Consensus Reference Beam Model.

Medical physics·2025
Same author

Value in the treatment of primary and metastatic liver tumors: comparative cost-analysis of transarterial chemoembolization to transarterial radioembolization.

HPB : the official journal of the International Hepato Pancreato Biliary Association·2025

The type of biopsy used for breast cancer diagnosis does not independently impact sentinel lymph node (SLN) metastasis risk. This finding is crucial for understanding nodal status in breast cancer staging.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Breast Cancer Research

Background:

  • Sentinel lymph node (SLN) status is critical for breast cancer staging and treatment decisions.
  • The influence of biopsy examination type on SLN status requires clarification.

Purpose of the Study:

  • To investigate whether the method of initial breast cancer biopsy independently affects sentinel lymph node (SLN) positivity.
  • To identify factors influencing SLN status in breast cancer patients.

Main Methods:

  • Prospective multicenter study analyzing data from 3853 breast cancer patients undergoing SLN biopsy and axillary node dissection.
  • Comparison of SLN positivity rates across different biopsy types: fine-needle, core-needle, excisional, and incisional.

Main Results:

Related Experiment Videos

  • Overall SLN positivity rate was 32%.
  • SLN positivity rates varied significantly by biopsy type (fine-needle: 45%, core-needle: 32%, excisional: 29%, incisional: 65%; P < .001).
  • Multivariate analysis indicated that biopsy type, along with histologic subtype, did not independently predict SLN status, while patient age, tumor size, palpability, number of SLNs removed, surgery type, and immunohistochemistry use were significant predictors.

Conclusions:

  • The type of biopsy examination does not independently influence the risk of nodal metastasis in breast cancer patients.
  • While initial biopsy methods show differing SLN positivity rates, these differences are not independent predictors of metastasis when other factors are considered.