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Macrocyclic polyesters. I. A novel class of 1,3-butandiol derivatives as potential antimicrobial agents
A M Fadda1, A M Maccioni, E Maccioni
1Dipartimento Farmaco Chimico Technologico, Università di Cagliari, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|January 1, 1992
Abstract:
This paper reports the synthesis of a novel class of macrocyclic tetraesters containing 1,3-butandiol sub-units by reacting the stannolan derivative of the diol with diacyl chloride. The structure of the possible isomers was assigned by spectroscopic data and comparison with samples otherwise prepared. Preliminary screening revealed that these compounds have low antimicrobial activity, although it is higher than that of the starting diol.