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Updated: Aug 15, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Thyroid maltoma: report of a case without coexistent Hashimoto's thyroiditis]
G Castronovo1, A Ciulla, G Tomasello
1Dipartimento di Chirurgia Generale, Urgenza e Trapianti d'Organo, Università degli Studi di Palermo, Palermo.
Abstract:
Maltomas of the thyroid are rare neoplasms that originate from parafollicular B lymphocytes and are often associated with autoimmune thyroiditis (Hashimoto's disease). The authors describe a case of a primary thyroid lymphoma in which no evidence for a previous thyroiditis could be found during clinical evaluation (clinical progression of the tumor, diagnostic studies, preoperative cytology, histology of the surgical specimen). Noteworthy was the development of a severe form of pure red cell aplasia (PRCA) about 6 months after the operation without detectable autoantibodies or signs of previous viral infection. The aplasia resolved completely with corticosteroid therapy.
