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Updated: May 5, 2026

Two-Photon-Based Photoactivation in Live Zebrafish Embryos
Published on: December 24, 2010
Innovation: Photoactivatable fluorescent proteins
Konstantin A Lukyanov1, Dmitry M Chudakov, Sergey Lukyanov
1Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia. kluk@ibch.ru
Abstract:
The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.
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