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Exocytosis upon osmotic swelling in human epithelial cells
Y Okada1, A Hazama, A Hashimoto
1Department of Physiology, Kyoto University Faculty of Medicine, Japan.
Biochimica Et Biophysica Acta
|June 11, 1992
Abstract:
Upon osmotic swelling human epithelial cells exhibited significant increases in the membrane capacitance. Evidence for exocytosis includes its dependency on temperature, cytosolic Ca2+ and ATP as well as its sensitivity to guanosine 5'-O-(3-thio)triphosphate (GTP gamma S) and N-ethylmaleimide (NEM). A role of the osmotic exocytosis in the subsequent cell volume regulation is suggested.