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Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
Human chorionic gonadotropin in cervical fluid as a predictor of miscarriage
Kayoko Takata1, Nobuhiko Suganuma, Hisae Wada
1Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, Japan. takata@hama-med.ac.jp
Objective:
To determine whether the concentration of hCG in cervical fluid can predict miscarriage during early pregnancy.
Design:
Prospective clinical study.
Setting:
University hospital.
Patient(S):
Ninety-nine women with singleton pregnancies, 17 of whom suffered a miscarriage.
Intervention(S):
None.
Main Outcome Measure(S):
Miscarriage and the cervical fluid/serum hCG concentration ratio.
Result(S):
With a cutoff value of 1.0, the sensitivity, specificity, and positive and negative predictive values of the cervical fluid/serum hCG concentration ratio for predicting miscarriage were 88.2%, 94.9%, 83.3%, and 96.6%, respectively.
Conclusion(S):
The cervical fluid/serum hCG concentration ratio might be a useful predictor of miscarriage during early pregnancy.
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