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Section E6 of the ACMG technical standards and guidelines: chromosome studies for acquired abnormalities

Betsy Hirsh1, Arthur R Brothman, Peter B Jacky

  • 1ACMG Laboratory Quality Assurance Cytogenetic Subcommittee, USA.

Genetics in Medicine : Official Journal of the American College of Medical Genetics
|September 20, 2005
PubMed
Abstract

No abstract available in PubMed .

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Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...

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