Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Non-compaction cardiomyopathy].

Heinrich Wieneke1, Till Neumann, Frank Breuckmann

  • 1Westdeutsches Herzzentrum, Klinik für Kardiologie, Universitätsklinikum, Essen. heinrich.wieneke@uni-essen.de

Herz
|September 20, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Silibinin promotes hepatocyte proliferation through PINK1/Parkin-mediated mitophagy to alleviate acetaminophen-induced liver injury.

Clinical and experimental medicine·2026
Same author

Correction: Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition.

Cell death & disease·2025
Same author

Effect of anticoagulation on the age distribution of thrombi in stroke patients with non-valvular atrial fibrillation.

BMJ neurology open·2025
Same author

Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition.

Cell death & disease·2025
Same author

Acute Prevention of the Heart Attack: The Identification of Prodromal Symptom Recognition as the "Rosetta Stone" in Decoding the Heart Attack Problem.

Critical pathways in cardiology·2025
Same author

ChatGPT-4 Performance on German Continuing Medical Education-Friend or Foe (Trick or Treat)? Protocol for a Randomized Controlled Trial.

JMIR research protocols·2025
Same journal

[Advancing cardiovascular prevention : Evidence-based design of healthy and sustainable food environments].

Herz·2026
Same journal

[Effects of air pollution on cardiovascular health].

Herz·2026
Same journal

[Heart and climate].

Herz·2026
Same journal

Multidimensional psychosocial screening in routine cardiac care: preliminary findings from a cross-sectional survey.

Herz·2026
Same journal

[Noise and the heart].

Herz·2026
Same journal

[The cardiovascular exposome: areas of action for prevention and practical cardiology].

Herz·2026
See all related articles

Isolated non-compaction of the ventricular myocardium (INVM) is a rare cardiomyopathy characterized by excessive left ventricular trabeculation. Its mechanism involves arrested cardiac myogenesis, leading to heart failure, arrhythmias, and thromboembolic events.

Area of Science:

  • Cardiology
  • Genetics
  • Pathology

Context:

  • Isolated non-compaction of the ventricular myocardium (INVM), also termed left ventricular hypertrabeculation or spongy myocardium, is a WHO-unclassified cardiomyopathy.
  • It is defined by prominent left ventricular trabeculation and deep intertrabecular recesses.

Purpose:

  • To describe the characteristics, pathogenesis, clinical manifestations, and therapy of isolated non-compaction of the ventricular myocardium.

Summary:

  • INVM is characterized by excessive trabeculation and deep recesses in the left ventricle.
  • The presumed pathomechanism involves an arrest in cardiac myogenesis, preserving embryonic myocardial morphology.
  • Clinical presentations frequently include congestive heart failure, ventricular arrhythmias, and systemic thromboembolic events.

Related Experiment Videos

Impact:

  • Understanding INVM's characteristics and pathogenesis aids in diagnosis and management.
  • Standard heart failure medical therapy is the current treatment approach for INVM.