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Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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Erythrocyte spectrin's chimeric E2/E3 ubiquitin conjugating/ligating activity

Y J Hsu1, W E Zimmer, S R Goodman

  • 1Institute of Biomedical Sciences and Technology, University of Texas at Dallas, Richardson, TX 75083, USA.

Cellular and Molecular Biology (Noisy-Le-Grand, France)
|September 21, 2005
PubMed
Summary

Human erythrocyte alpha-spectrin possesses ubiquitin conjugating enzyme (E2) and ubiquitin protein ligase (E3) activities. Cysteine 2071 and cysteine 2100 residues are critical for these spectrin E2/E3 enzymatic functions.

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