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Updated: Aug 15, 2026

A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
Published on: May 3, 2021
Surveillance in patients with sarcoma of the extremities
1The Royal Orthopaedic Hospital, Northfield, Birmingham B31 2AP, UK. paul.cool@rjah.nhs.uk
Aim:
To evaluate the efficiency of our follow-up regime for patients with sarcoma of the extremities.
Methods:
We have reviewed our follow-up policy in 480 patients with non-metastatic bone or soft tissue sarcomas and with more than 5 years of follow-up.
Results:
We detected 24% of the soft tissue sarcoma recurrences and 38% of the bone tumour recurrences. We detected 67% of the pulmonary metastases before they became symptomatic. Only 11% of those patients who developed metastases were cured, as were only 26% of those who developed local recurrence.
Conclusions:
This study shows that our surveillance programme detects most metastases, but only about one third of the local recurrences.