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Cleft lip and palate in Western Slovakia in the years 1985-2000

R Bánsky1, E Machácová, J Fedeles

  • 1Department of Plastic Surgery, Faculty of Medicine, Commenius University and General Hospital Ruzinov, Bratislava, Slovak Republic. plast@orangemail.sk

Acta Chirurgiae Plasticae
|September 22, 2005
PubMed

Insights

This study assessed orofacial clefts (OC) incidence in Western Slovakia, finding 1.64 cases per 1000 live births. Bratislava had a higher OC rate than the wider region, with cleft lip and palate being most common.

Area of Science:

  • Medical research
  • Public health
  • Pediatric surgery

Background:

  • Orofacial clefts (OC) represent frequent congenital anomalies.
  • Understanding regional incidence is crucial for public health initiatives.

Purpose of the Study:

  • To determine the incidence of orofacial clefts in Western Slovakia.
  • To compare OC rates between Bratislava and the surrounding region.
  • To identify common OC types and demographic patterns.

Main Methods:

  • Retrospective analysis of infant case records from 1985-2000.
  • Inclusion criteria: live births in Bratislava and Western Slovakia operated on for OC.
  • Data collected from the Department of Plastic Surgery, Faculty of Medicine, Comenius University.

Main Results:

  • A total incidence of 1.64 per 1000 live births was recorded.
  • Incidence was significantly higher in Bratislava compared to Western Slovakia.
  • Cleft lip and palate (CLP) was the most frequent type, with a male-to-female ratio of 1.16:1.

Conclusions:

  • Significant variations in OC incidence were observed across districts.
  • These findings suggest potential genetic or environmental factors influencing OC prevalence.
  • Further investigation into endemic factors is warranted for targeted interventions.

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