Related Experiment Video
Updated: Aug 15, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
[Use of psychotherapy in patients with combined epileptic and nonepileptic seizures]
1Neurologická klinika LF UK a FN, Plzen. chmelarova@fnplzen.cz
Abstract:
Nonepileptic seizures can be divided according to the aetiology of their origin into two main groups: as somatically or psychogenically determined. The group of psychogenical nonepileptic seizures has not been clearly defined and it has no generally accepted terminology. In the model used in this article, psychogenic seizures can be classified according to the conscious and unconscious control. Differential diagnostics is difficult and an interdisciplinary cooperation is required. The therapy is problematical; especially the treatment of patients with combined seizures that could be therefore considered as pharmaco-resistant. In such cases it is necessary to combine antiepileptic medication with psychotherapeutic techniques. The psychotherapeutic techniques used in the presented case are, among others, following: Rogers's psychotherapy, techniques of self-regulation and relaxation, and Leuner's imaginative technique. Significant seizure reduction was achieved after two years of the joint effort of the neurologist and psychologist treating a 34-year-old woman who suffered from combined seizures. She was temporary regarded as pharmaco-resistant with a prominent anxiety disorder verging to social phobia. After four years of treatment, she has had no seizures for the recent eight months, she had no problems in the social communication either and she has been also without the characteristic anxiety features.
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Electroconvulsive Therapy
Psychosis: Goals of Pharmacotherapy
Antiepileptic Drugs: GABAergic Pathway Potentiators
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for their...
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
Epilepsy ll: Types

