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Updated: Aug 15, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
[Efficacy of tracrolimus 0.1% ointment in prurigo]
Hae-Hyuk Lee1, Wolfram Sterry, Margitta Worm
1Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin.
Background:
Potent topical corticosteroids are used the intense pruritus in prurigo diseases. Their long-term application leads to local side effects such as atrophy and telangiectasia.
Patients And Methods:
We treated 6 women (average age 64 years) with chronic prurigo with tacrolimus 0.1 % ointment (Protopic) to evaluate its efficacy in this clinical setting. Tacrolimus 0.1% ointment was applied twice a day for 4 weeks.
Results:
After one week, both clinical improvement and reduced pruritus were observed in all patients.
Conclusion:
Tacrolimus 0.1% ointment represents a therapeutic option for the treatment of prurigo.