Different clinical features of aortic intramural hematoma versus dissection involving the descending thoracic aorta

Mariano Falconi1, Pablo Oberti, Juan Krauss

  • 1Division of Cardiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. mariano.falconi@hospitalitaliano.org.ar

Insights

Aortic intramural hematoma (IMH) of the descending aorta can lead to complications like dissection. Medical management with close imaging and timely surgery for complications improves patient outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • Aortic intramural hematoma (IMH) and aortic dissection (AD) are distinct aortic emergencies.
  • The clinical course and outcomes of IMH involving the descending aorta, particularly in relation to flow communication, require further elucidation compared to AD.

Purpose of the Study:

  • To test the hypothesis that the absence of flow communication in descending thoracic aorta IMH leads to a different clinical course than AD.
  • To compare the clinical presentation, predictors of complications, treatment strategies, and outcomes between IMH and AD of the descending thoracic aorta.

Main Methods:

  • Prospective evaluation of clinical and echocardiographic data.
  • Comparison of 76 patients with AD and 27 patients with IMH of the descending thoracic aorta.
  • Analysis of follow-up data including complications, interventions, and survival rates.

Main Results:

  • No significant differences in age, gender, or initial clinical presentation between IMH and AD groups.
  • Aortic diameter >5 cm and persistent back pain were common predictors of complications in both groups.
  • Surgical treatment was more frequent in AD, with higher mortality in surgically treated AD patients compared to IMH. Medical treatment showed similar mortality rates for both conditions. IMH showed resolution/regression in 47%, aortic enlargement in 26%, and progression to AD in 13% over follow-up. Three-year survival rates were comparable (82% for IMH vs. 75% for AD).

Conclusions:

  • Descending thoracic aorta IMH has a notable rate of complications, including progression to dissection and aneurysm formation.
  • Medical management, coupled with frequent imaging surveillance and elective surgery for complications, is crucial for optimal patient care.
  • While distinct, IMH and AD share some predictors of complications, and outcomes can be managed effectively with a tailored approach.
Abstract

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
The Aorta01:14

The Aorta

The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...