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Updated: Aug 15, 2026

Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings
Published on: August 19, 2021
Kinetics of the thermal inactivation of the Lactococcus lactis bacteriophage P008
Mareile Müller-Merbach1, Horst Neve, Jörg Hinrichs
1Institute for Food Technology, University of Hohenheim, Garbenstr. 21, D-70599 Stuttgart, Germany. MareileMM@web.de
Abstract:
The thermal resistance of the lactococcal bacteriophage P008 was investigated between 55 and 80 degrees C. Inactivation kinetics revealed an order of reaction above 1 and could be determined by a non-1st-order regression model. Phage inactivation was influenced by the medium (milk and Ca-M17-broth). Within the investigated temperature range, milk had a protective effect on phage P008. This was reflected in the rate constant and in the activation energy. Thermal phage inactivation studies reported in literature were re-analysed using non-1st-order regression. The obtained kinetic parameters showed that phage P008 belongs to the most heat resistant lactococcal phages investigated so far.
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