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External validation of the ICH score.

Jennifer L Clarke¹, S Claiborne Johnston, Mary Farrant

¹Department of Neurology, University of California, San Francisco, and San Francisco General Hospital, CA 94110, USA.

Neurocritical Care

|September 22, 2005

Summary

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The ICH score accurately predicts outcomes in patients with intracerebral hemorrhage (ICH). This validated grading scale aids in risk stratification and can standardize clinical studies for nontraumatic ICH.

Area of Science:

Neurology
Clinical Medicine
Medical Informatics

Background:

The Intracerebral Hemorrhage (ICH) score is a validated clinical grading scale.
It comprises five components: Glasgow Coma Scale score, ICH volume, intraventricular hemorrhage, infratentorial origin, and age.
External validation of the ICH score is necessary.

Purpose of the Study:

To validate the ICH score in an independent patient cohort.
To determine if the ICH score accurately risk-stratifies patients with nontraumatic ICH.

Main Methods:

Retrospective review of 175 patients with acute ICH from 1998-2000.
Outcome assessment based on 30-day mortality.
Analysis of ICH score correlation with mortality.

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Main Results:

Thirty-day mortality was 40% in the cohort.
Increasing ICH scores correlated significantly with increased 30-day mortality (p<0.01).
Receiver operating characteristic curves demonstrated similar performance to the original cohort.

Conclusions:

The ICH score accurately stratifies outcomes in an external patient cohort.
The ICH score is a validated, easily applicable tool for risk stratification at presentation.
It can standardize clinical treatment protocols and research studies for ICH.