Related Experiment Video
Updated: Aug 15, 2026

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
Unilateral third nerve palsy caused by Guillain-Barré Syndrome
Erik K St Louis1, Daniel M Jacobson
1Department of Neurology, Marshfield Clinic, Marshfield, WI, USA. erik-stlouis@uiowa.edu
Background:
Highly asymmetric clinical signs in a patient suggest the need for caution in making the diagnosis of Guillain-Barré Syndrome (GBS).
Methods:
Case report and literature review. We present a case of strictly unilateral left third cranial nerve palsy in a patient with GBS, review other highly asymmetrical cranial nerve palsies previously reported in this condition, and suggest an appropriate alternative differential diagnosis.
Conclusion:
Unilateral third cranial nerve palsy is an exceptionally rare manifestation of GBS, expanding the spectrum of clinical signs and neuraxis involvement that may be seen in the condition.
