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Coronary angiojet catheterization for the management of dural venous sinus thrombosis. Technical note
Celso Agner1, Eric M Deshaies, Gary L Bernardini
1Department of Neurology, Albany Medical Center, Albany, New York 12208, USA.
Insights
This study presents a novel combined treatment for deep venous sinus thrombosis. Direct thrombolysis and mechanical thrombectomy successfully restored venous flow and led to complete patient recovery.
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Radiology
Background:
- Deep venous sinus thrombosis often requires systemic anticoagulation.
- Extensive cases may necessitate combined treatments like thrombolysis and mechanical thrombectomy.
- Standard treatments can be insufficient in severe deep venous sinus thrombosis.
Observation:
- A patient presented with stroke-like symptoms and was diagnosed with extensive DVST.
- Neurological status worsened despite systemic heparinization.
Findings:
- Direct thrombolysis with alteplase and mechanical thrombectomy using an AngioJet system successfully restored venous flow.
- A 0.014-in wire facilitated recanalization from the femoral vein through the sinuses.
Implications:
- This combined endovascular technique offers a viable alternative for complex DVST cases.
- Successful treatment led to complete neurological recovery and excellent angiographic outcomes.
Abstract:
In most cases of deep venous sinus thrombosis, systemic anticoagulation represents the initial treatment of choice for preventing propagation of a clot in the dural sinuses. In patients with deep or extensive venous sinus thrombosis, a combination of treatment modalities may be required including systemic anticoagulation, selective venous thrombolysis, and mechanical thrombectomy. In the current study the authors report on a patient who presented with the acute onset of headache, vomiting, a depressed level of consciousness, and a left hemiparesis and in whom a right middle cerebral artery (MCA) territory ischemic stroke with hemorrhagic conversion was initially diagnosed. Results of diagnostic cerebral angiography demonstrated a patent right MCA and a deep venous sinus thrombosis involving most of the dural sinuses. Despite adequate systemic heparinization, the patient's neurological condition deteriorated and direct administration of alteplase into the transverse sinus in conjunction with mechanical clot disruption using a coronary AngioJet was required. Venous flow was successfully reestablished in the deep and superficial venous sinuses by using a 0.014-in exchange wire routed from the right common femoral vein through the sinuses and out the left common femoral vein. Excellent angiographic results were obtained, and the patient had recovered completely by the 7-month follow up.
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