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Published on: September 11, 2012
ANCA-associated vasculitis as paraneoplastic syndrome with colon cancer: a case report
L Diez-Porres1, J J Rios-Blanco, A Robles-Marhuenda
1Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain. jjrios@movistar.com
Abstract:
Coexistence of a vasculitis and a neoplastic disease is rare and the pathogenesis is unknown. Most of these associations refer to leukocytoclastic or poliarteritis nodosa (PAN)-type vasculitis and hematological malignancies. There are few reports of vasculitis in patients with solid tumours and there are also few reports of paraneoplastic ANCA-associated vasculitis. We report a case of p-ANCA-positive vasculitis with peripheral nerve involvement associated with a colon cancer. Vasculitis resolved after corticoid treatment and surgical removal of the tumour.
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