Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multicentre physiological reference values for some urinary component-to-creatinine (creatininium) concentration

Xavier Fuentes-Arderiu1, Roser Mas-Serra, Carmen de-Nó-Lengaran

  • 1Laboratori Clínic, IDIBELL - Hospital Universitari de Bellvitge, Feixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Catalonia, Spain. xfa@csub.scs.es

Clinical Chemistry and Laboratory Medicine
|September 24, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic factors for the severity of SARS-CoV-2 infection.

Advances in laboratory medicine·2023
Same author

Uncertainty of Measurement in Clinical Microbiology.

EJIFCC·2018
Same author

Uncertainty of Measurement and Heteroscedasticity.

EJIFCC·2018
Same author

Bio-Metrological Uncertainty In Clinical Laboratory Sciences.

EJIFCC·2018
Same author

Properties and units in the clinical laboratory sciences part XXIV. Properties and units in clinical molecular genetics (technical report 2017).

Clinica chimica acta; international journal of clinical chemistry·2018
Same author

Estimating Systematic Error of Measurement Procedures of Lipid Quantities.

EJIFCC·2018

This study established multicentre reference values for urinary analytes like albumin and electrolytes in Spain. These values, measured using specific analysers, provide crucial benchmarks for clinical laboratory diagnostics.

Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Biochemistry

Background:

  • Establishing reliable reference values is crucial for accurate clinical laboratory diagnostics.
  • Urinary component-to-creatinine ratios are commonly used to normalize results due to variations in hydration.
  • Standardization across different laboratories and analytical platforms is a persistent challenge.

Purpose of the Study:

  • To determine multicentre reference values for urinary component-to-creatinine ratios in Spain.
  • To establish reference ranges for specific urinary analytes including albumin, electrolytes, and urea.
  • To validate the use of RD/Hitachi analysers for these measurements.

Main Methods:

  • A collaborative study involving nine clinical laboratories across Spain.

Related Experiment Videos

  • Measurement of urinary albumin, calcium, chloride, magnesium, phosphate, potassium, protein, sodium, urate, and urea.
  • Utilisation of first morning urine samples and RD/Hitachi analysers.
  • Parametric estimation of multicentre reference limits after mathematical data transformation.

    • Main Results:

    • Reference values were successfully generated for multiple urinary analytes.
    • The study provides a consolidated set of reference limits derived from diverse Spanish laboratories.
    • Data transformation and parametric estimation were employed to establish robust reference ranges.

    Conclusions:

    • The collaborative effort successfully produced multicentre reference values for key urinary analytes.
    • These reference values are essential for improving the consistency and accuracy of clinical laboratory testing in Spain.
    • The findings support the use of RD/Hitachi analysers for routine urinary analysis.