Related Experiment Video
Updated: Jul 17, 2026
06:15
Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
Published on: November 10, 2023
The upper airway in Weaver syndrome
Mark W Crawford1, Denise Rohan
1Department of Anesthesia, The Hospital for Sick Children, University of Toronto, Ontario, Canada. mark.crawford@sickkids.ca
Paediatric Anaesthesia
|September 24, 2005
Summary
Weaver syndrome, a rare genetic disorder, presents anesthetic challenges. This study found tracheal intubation was easier in older children, suggesting age-related improvement in airway management for Weaver syndrome patients.
Area of Science:
- Pediatric Anesthesiology
- Medical Genetics
- Craniofacial Abnormalities
Background:
- Weaver syndrome is a rare genetic disorder characterized by skeletal overgrowth and craniofacial abnormalities.
- A significant anesthetic concern in Weaver syndrome is difficult tracheal intubation due to micrognathia and laryngeal positioning.
Observation:
- This report details the anesthetic management of two children with Weaver syndrome undergoing dental surgery.
- Tracheal intubation was successfully achieved with relative ease in both patients.
Findings:
- Contrary to previous literature, intubation difficulty may not be a constant feature of Weaver syndrome.
- The ease of intubation suggests an age-related improvement, potentially linked to mandibular growth.
Implications:
- Anesthetic management for Weaver syndrome may need to consider patient age.
- Further research is warranted to confirm the age-related nature of airway challenges in Weaver syndrome.
- Findings may inform anesthetic strategies for similar micrognathic syndromes.
Related Concept Videos
01:21Larynx
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
01:22Trachea
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
01:29Anatomy of Respiratory System I: Upper Respiratory Tract
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
01:29Suctioning the Nasopharyngeal Airway
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
01:25Suctioning the Oropharyngeal Airway
In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
01:30Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway interventions are...