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Updated: Jul 16, 2026

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
Published on: August 16, 2012
Architecture and design of the nuclear pore complex
J E Hinshaw1, B O Carragher, R A Milligan
1Department of Cell Biology, Scripps Research Institute, La Jolla, California 92037.
Abstract:
A three-dimensional analysis of the nuclear pore complex reveals the underlying, highly symmetric framework of this supramolecular assembly, how it is anchored in the nuclear membrane, and how it is built from many distinct, interconnected subunits. The arrangement of the subunits within the membrane pore creates a large central channel, through which active nucleocytoplasmic transport is known to occur, and eight smaller peripheral channels that are probable routes for passive diffusion of ions and small molecules.
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