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Implementation of laboratory order data in BioSense Early Event Detection and Situation Awareness System.

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  • 1CDC, Atlanta, Georgia 30333, USA. HMa@cdc.gov

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Laboratory test order data from LabCorp can enhance early outbreak detection. Grouping these orders into standard syndrome categories improves public health surveillance systems like BioSense.

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Area of Science:

  • Public Health Surveillance
  • Infectious Disease Epidemiology
  • Health Informatics

Background:

  • Laboratory test orders serve as a crucial early data source for detecting disease outbreaks.
  • The Centers for Disease Control and Prevention (CDC) receives laboratory order data from Laboratory Corporation of America (LabCorp) in HL7 format.
  • This data is intended for integration into the BioSense Early Event Detection and Situation Awareness System.

Purpose of the Study:

  • To develop a standardized method for categorizing laboratory test orders to aid in early outbreak detection.
  • To create a consensus-based taxonomy for laboratory order data.
  • To enhance the utility of laboratory order data for public health surveillance.

Main Methods:

  • A consensus panel grouped test orders into eight standard syndrome categories based on expert opinion.
  • A laboratory order taxonomy with five main classes was developed and utilized.
  • International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes were used to understand reasons for test orders.

Main Results:

  • The study categorized laboratory order codes into eight syndrome groups: fever (53), respiratory (53), gastrointestinal (27), neurological (35), rash (37), lymphadenitis (20), localized cutaneous lesion (11), and specific infection (63).
  • This categorization provides a quantitative overview of laboratory test order distributions across different syndromes.

Conclusions:

  • Daily analysis of laboratory order data within the BioSense system allows for the evaluation of code distribution across syndrome groups.
  • This evaluation facilitates ongoing refinement and modification of the data mapping process.
  • The developed syndrome categories enhance the value of laboratory order data for real-time public health monitoring.