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Published on: March 2, 2011
[Detection and measurement of interleukin-8 in peri-implant crevicular fluid]
De-Rong Zou1, Hong Zhu, Xiao-Hui Qu
1Dept. of Stomatology, Shanghai Jiao Tong University, Affiliated Shanghai Sixth People's Hospital, Shanghai 200233, China.
Objective:
Gingival crevicular fluid (GCF) analysis of various inflammatory mediators has been investigated as a means of providing objective criteria of peri-implant tissue health. In this report, the crevicular fluid levels of interleukin-8 (IL-8), GCF volume and clinical parameters were studied.
Methods:
GCF was sampled from 35 healthy and 35 inflamed sites of implantation patients. IL-8 levels were analysed using ABC-ELISA. Clinical parameters were measured, and data analysis was performed using the software package SPSS10.0.
Results:
Significant difference was observed between healthy implant sites and peri-implantitis sites. GCF volume was positively correlated with PD, PI, GI and MOB. The total amount of IL-8 was positively correlated with PD and GI.
Conclusion:
This investigation suggested that GCF volume and IL-8 cytokine may be of value as a diagnostic and prognostic marker for peri-implantitis.
