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Quantitative Analysis of Aspergillus nidulans Growth Rate using Live Microscopy and Open-Source Software
Published on: July 24, 2021
Correlation between in vitro growth rate and in vivo virulence in Aspergillus fumigatus
Derek Paisley1, Geoffrey D Robson, David W Denning
1Clinical Sciences Building, Hope Hospital, Salford, UK.
Medical Mycology
|September 24, 2005
Abstract:
We describe a kinetic microbroth method of measuring the growth rate of Aspergillus fumigatus spectrophotometrically. Using this method, growth rates were determined for nine A. fumigatus isolates for which an LD90 value in immunosuppressed CD-1 mice had previously been obtained. Comparison of the growth rates and LD90 values of these isolates suggests that a correlation exists between the two parameters.
