Related Experiment Video
Updated: May 3, 2026
08:53
Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
Published on: August 31, 2016
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Canadian stem cell scientists take the prize.
1Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA. ssharkis@jhmi.edu
Cell
|September 24, 2005
Summary
Ernest A. McCulloch and James E. Till received the Lasker Award for defining stem cell properties. Their research identified stem cells
Area of Science:
- Hematology
- Cell Biology
- Genetics
Background:
- Stem cells are crucial for development and tissue repair.
- Understanding stem cell properties is fundamental to regenerative medicine.
Purpose of the Study:
- To honor the foundational work of Ernest A. McCulloch and James E. Till.
- To highlight the definition of stem cell self-renewal and differentiation.
Main Methods:
- Pioneering research in the 1960s.
- Experimental studies on hematopoietic stem cells.
Main Results:
- Defined the key characteristics of stem cells.
- Established the concepts of self-renewal and differentiation.
Conclusions:
- McCulloch and Till's work laid the groundwork for stem cell research.
- Their discoveries remain central to the field of stem cell biology.
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