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Related Experiment Videos

The External RNA Controls Consortium: a progress report.

Shawn C Baker1, Steven R Bauer, Richard P Beyer

  • 1Illumina, Inc., 9885 Towne Centre Drive, San Diego, California 92121, USA.

Nature Methods
|September 24, 2005
PubMed
Summary

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Standardized controls enhance data quality and acceptance in research and clinical labs. The External RNA Controls Consortium (ERCC) is creating industry-wide standards for expression assays.

Area of Science:

  • Molecular Biology
  • Biotechnology
  • Genomics

Background:

  • Standardized controls are crucial for validating data quality in research, preclinical, and clinical laboratory settings.
  • Best practice guidelines facilitate the acceptance of experimental data across scientific disciplines.

Purpose of the Study:

  • To introduce the development of industry-wide standard controls for expression assays.
  • To highlight the role of the External RNA Controls Consortium (ERCC) in establishing these standards.

Main Methods:

  • Development of commonly agreed-upon controls.
  • Testing of these controls for reliability and consistency.

Main Results:

  • The External RNA Controls Consortium (ERCC) is creating a universally accepted set of controls.

Related Experiment Videos

  • These controls aim to ensure consistent and reliable data evaluation in expression assays.

    • Conclusions:

    • The ERCC's initiative represents a significant step towards industry-wide standardization in expression assays.
    • Implementing these standard controls will advance the reproducibility and acceptance of laboratory data.