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Updated: Aug 15, 2026

Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
Published on: February 10, 2023
Therapeutic pericardiocentesis in the dog and cat
Josh Gidlewski1, Jean-Paul Petrie
1Garden State Veterinary Specialists, Tinton Falls, NJ 07753, USA. cardiovet@gmail.com
Insights
Pericardial effusion in dogs often stems from cancer or idiopathic causes, leading to cardiac tamponade. Pericardiocentesis is a key procedure to relieve pressure and diagnose the cause, with rare complications.
Area of Science:
- Veterinary Cardiology
- Internal Medicine
Background:
- Pericardial effusion can cause life-threatening hemodynamic compromise and cardiac tamponade.
- In dogs, cardiac neoplasia and idiopathic pericardial effusion (IPE) are primary indications for pericardiocentesis.
- Common clinical signs include lethargy, dyspnea, anorexia, collapse, and abdominal distension.
Purpose of the Study:
- To review the causes and diagnosis of pericardial effusion in dogs.
- To discuss the role of pericardiocentesis in managing cardiac tamponade.
- To highlight potential complications associated with pericardiocentesis.
Main Methods:
- Review of current literature on canine pericardial effusion.
- Discussion of diagnostic approaches, including fluid analysis.
- Evaluation of pericardiocentesis as a therapeutic and diagnostic tool.
Main Results:
- Cardiac neoplasia (hemangiosarcoma, chemodectoma) and IPE are leading causes of pericardial effusion requiring pericardiocentesis in dogs.
- Pericardiocentesis effectively stabilizes animals with cardiac tamponade and aids diagnosis.
- Serious complications from pericardiocentesis are uncommon.
Conclusions:
- Pericardial effusion is a significant concern in canine cardiology, often requiring pericardiocentesis.
- Accurate diagnosis and prompt management are crucial for improving outcomes.
- Understanding potential complications ensures safe and effective patient care.
Abstract:
Pericardial effusion is a potentially life-threatening problem leading to a rise in the intrapericardial pressure resulting in varying degrees of hemodynamic compromise. Cardiac tamponade occurs when the intrapericardial pressure equals or exceeds right ventricular diastolic filling pressures leading to a decreased cardiac output. In dogs, the most common causes of pericardial effusion that require pericardiocentesis are cardiac neoplasia and idiopathic pericardial effusion (IPE). The incidence of cardiac neoplasia in dogs is low, and it is rare in cats. In dogs, hemangiosarcoma and chemodectoma are the two most common types of cardiac neoplasia. In cats, lymphosarcoma is the most common form of cardiac neoplasia, but they are more likely to develop pericardial effusion secondary to congestive heart failure or feline infectious peritonitis. Common histories include lethargy, dyspnea, anorexia, collapse, and abdominal distension. Pericardiocentesis is used to stabilize animals with life-threatening cardiac tamponade, relieve the pressure leading to right-sided heart failure, and obtain fluid samples for diagnostic evaluation. The fluid should be quantified and characterized. Serious complications associated with pericardiocentesis are rare. Complications include cardiac puncture, arrhythmias, and laceration of a tumor or coronary artery resulting in intrapericardial hemorrhage or sudden death.
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