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Patent foramen ovale.

Yun-Ching Fu¹, Ziyad M Hijazi

¹Department of Pediatrics, Taichung Veterans General Hospital, National Yang-Ming University, Taichung, Taiwan. ivanfu@vghtc.gov.tw

Expert Review of Cardiovascular Therapy

|September 27, 2005

Summary

This summary is machine-generated.

Patent foramen ovale closure is being studied as a stroke treatment. Current evidence does not confirm if device closure is better than medical therapy alone for cryptogenic stroke patients.

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Area of Science:

Cardiology
Neurology
Medical Devices

Background:

Patent foramen ovale (PFO) is a potential cause of cryptogenic stroke.
Medical therapy is the current standard of care for stroke prevention in PFO patients.

Observation:

The role of PFO in cryptogenic stroke remains controversial.
Device closure aims to prevent paradoxical embolism through the PFO.

Findings:

Evidence comparing PFO closure devices to medical therapy is limited.
Ongoing randomized controlled trials are investigating the efficacy of PFO closure.

Implications:

Results from ongoing trials will inform clinical guidelines for PFO management.
Optimal treatment strategies for cryptogenic stroke in PFO patients are under investigation.