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Dual chamber epicardial pacing for the failing atriopulmonary Fontan patient
Ali Dodge-Khatami1, Mariette Rahn, René Prêtre
1Division of Cardiovascular Surgery, University Children's Hospital Zürich, Zürich, Switzerland. ali.dodge-khatami@kispi.unizh.ch
Insights
Dual chamber pacing offers a temporary solution for Fontan circulation patients experiencing arrhythmias or heart failure, improving hemodynamics and symptoms while delaying necessary conversion surgery.
Area of Science:
- Pediatric Cardiology
- Cardiac Electrophysiology
- Congenital Heart Disease Surgery
Background:
- Atriopulmonary Fontan circulation is associated with complications like arrhythmias, heart failure, and protein-losing enteropathy.
- These complications often necessitate conversion surgery, but patients may hesitate due to fear.
Purpose of the Study:
- To evaluate dual chamber pacing as a temporizing measure in patients with atriopulmonary Fontan connection and sinus node dysfunction.
- To assess the safety and efficacy of epicardial pacemaker systems in this patient population.
Main Methods:
- Nine pediatric patients (6-18 years) with atriopulmonary Fontan connection and sinus node dysfunction received dual chamber epicardial pacemakers.
- Indications included refractory arrhythmias, protein-losing enteropathy, heart failure, and exercise intolerance.
- Data were compared pre- and post-pacemaker implantation.
Main Results:
- No mortality or morbidity was observed.
- Lead survival was 100% at a mean follow-up of 3.3 years, with stable or improved pacing characteristics.
- Arrhythmias resolved in all patients, and medication was discontinued in three.
- Protein-losing enteropathy, exercise intolerance, and heart failure symptoms showed improvement.
Conclusions:
- Dual chamber pacing effectively improves single ventricle hemodynamics and manages decompensated Fontan patients.
- It serves as a valuable time-buying strategy for patients delaying conversion surgery.
- Left lateral thoracotomy is a safe and reliable approach for durable epicardial pacing in complex cases.
Background:
The atriopulmonary Fontan circulation leads to arrhythmias, heart failure, or protein-losing enteropathy, eventually requiring conversion. In hesitant patients, we evaluated the effect of dual chamber pacing as a time-buying measure.
Methods:
Between 1997 and 2004, 9 patients (aged, 6 to 18 years) with an atriopulmonary Fontan connection and sinus node dysfunction received dual chamber epicardial pacemaker systems. Indications included refractory arrhythmias (n = 5), protein-losing enteropathy (n = 2), heart failure with effusions (n = 1), and exercise intolerance (n = 2). Data were compared between hospital discharge after pacemaker implantation and last follow-up.
Results:
There was no mortality or morbidity. At a follow-up of 3.3 +/- 1.0 years, lead survival was 100%. Both atrial (impedance = 683 +/- 40 Ohm; threshold = 0.8 +/- 0.1 V at 0.5 ms; sensing P waves = 3.3 +/- 0.8 mV) and ventricular (impedance = 630 +/- 68 Ohm; threshold = 1.3 +/- 0.3 V at 0.5 ms; sensing R waves = 8.7 +/- 2.5 mV) leads retained satisfactory pacing characteristics at last control, better than those at discharge. Arrhythmias subsided in all instances and no longer required medication in 3 patients. Protein-losing enteropathy improved temporarily in 1 patient and disappeared in another. Exercise intolerance diminished, and heart failure was controlled.
Conclusions:
Although most atriopulmonary Fontan circulations will need conversion with arrhythmia surgery, patients may delay out of fear. Dual chamber pacing improves single ventricle hemodynamics and can help decompensated Fontan patients. In a multiple-redo setting, a left lateral thoracotomy provides safe access and allows for quantitatively reliable and durable epicardial pacing.
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