Related Experiment Video
Updated: Aug 15, 2026

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Non-invasive cardiac output determination by two-dimensional independent Doppler during and after cardiac surgery
Karsten Knobloch1, Artur Lichtenberg, Michael Winterhalter
1Department of Trauma Surgery, Medical School Hannover, Hannover, Germany. kknobi@yahoo.com
Insights
A novel noninvasive Doppler technique accurately measures cardiac output (CO) in postcardiac surgery patients. This method, using the Ultrasonic Cardiac Output Monitoring (USCOM) device, offers a safe alternative to invasive monitoring.
Area of Science:
- Cardiology
- Critical Care Medicine
- Medical Devices
Background:
- Accurate cardiac output (CO) monitoring is crucial in postcardiac surgery intensive care units (ICUs).
- Invasive methods, such as Swan-Ganz catheterization, carry potential complications.
- Noninvasive techniques are sought to provide reliable CO and stroke volume (SV) data.
Purpose of the Study:
- To compare noninvasive CO measurements using a novel Doppler technique (USCOM) with invasive CO measurements.
- To evaluate the agreement and correlation between the USCOM device and the Swan-Ganz catheter in postcardiac surgery patients.
Main Methods:
- Prospective study of 36 patients undergoing coronary revascularization.
- Paired measurements of CO and SV using the noninvasive USCOM device and invasive Swan-Ganz catheter.
- Intraoperative direct insonation of the right ventricular outflow tract for comparison.
Main Results:
- Excellent agreement between noninvasive (USCOM) and invasive (Swan-Ganz) CO measurements (r = 0.870; p < 0.01).
- Mean difference between methods was minimal (-0.23 +/- 1.01 L/min) across a wide CO range.
- Central venous saturation correlated significantly with both noninvasive and invasive CO measurements.
Conclusions:
- The USCOM device provides accurate, noninvasive, beat-to-beat CO and SV measurements in postcardiac surgery patients.
- USCOM offers a safe alternative to invasive right heart catheterization, avoiding associated complications.
- The findings support the clinical utility of USCOM for hemodynamic monitoring in this patient population.
Purpose:
This study was to compare noninvasive measurement of cardiac output (CO) using a novel Doppler technique with invasive CO measurements in the postcardiac surgical intensive care unit.
Description:
Thirty-six patients (67.2 +/- 10 years, New York Heart Association functional class 3.1 +/- 0.3) undergoing coronary revascularization were prospectively examined postoperatively. One hundred eighty paired CO and stroke volume measurements were compared from the noninvasive USCOM device (Sydney, Australia) and the invasive Swan-Ganz catheter at varying COs. Eighteen measurements were performed intraoperatively by direct insonation of the right ventricular outflow tract.
Evaluation:
Mean noninvasive and invasive CO values were 5.15 +/- 1.98 L/min and 4.92 +/- 2.0 L/min, respectively (r = 0.870; p < 0.01). The mean difference between methods was -0.23 +/- 1.01 L/min greater than a range of CO values from 2.5 to 9.9 L/min. Mean central venous saturation percentage was 72 +/- 9%, correlating with both noninvasive and invasive CO (r = 0.474 and 0.606, respectively, p < 0.01). Intraoperatively, both direct and invasive CO were identical.
Conclusions:
Using the ultrasonic cardiac output monitoring (USCOM) device it is possible to determine noninvasive beat-to-beat CO in postcardiac surgery patients without the possible complications associated with invasive right heart catheterization. The USCOM CO and stroke volume showed a very good agreement with invasive Swan-Ganz measures and correlated with central venous saturation percentage.
Related Concept Videos
Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Cardiac Catheterization II: Right Heart Catheterization
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac output averages...