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Hand involvement in paraneoplastic syndrome: a case report
Pablo De Carli1, Jorge Boretto, Walter Bourgeois
1Hand and Upper Extremity Department, Prof Dr Carlos Ottolenghi Institute, Italian Hospital of Buenos Aires, Buenos Aires, Argentina.
The Journal of Hand Surgery
|September 27, 2005
Summary
Paraneoplastic syndromes can manifest as skin changes linked to cancer. This case shows hand contractures improving after gastric cancer surgery, suggesting a paraneoplastic link.
Area of Science:
- Oncology
- Dermatology
- Gastroenterology
Background:
- Cutaneous paraneoplastic syndromes represent a diverse group of clinical manifestations associated with underlying malignancies.
- Early recognition is crucial for timely cancer diagnosis and management.
Observation:
- A 76-year-old man presented with severe finger and thumb contractures, pain, and hypersensitivity.
- These symptoms significantly impacted hand function and quality of life.
Findings:
- The patient was diagnosed with gastric carcinoma with colonic metastasis.
- Surgical resection of the gastrointestinal tumors led to a notable improvement in hand contractures and pain.
Implications:
- This case highlights the importance of considering paraneoplastic syndromes in patients with unexplained neurological or musculoskeletal symptoms.
- The resolution of symptoms post-tumor resection strongly suggests a paraneoplastic etiology, emphasizing the link between cancer and dermatologic manifestations.