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Intramandibular inflammatory myofibroblastic tumor--a true neoplasm or reactive lesion?
Catherine F Poh1, Robert W Priddy, Darren M Dahlman
1Oral Medicine Oral Pathology, University of British Columbia Faculty of Dentistry, Vancouver, Canada.
Objective:
Inflammatory myofibroblastic tumor (IMT) is an uncommon lesion reported to arise in various organs and by convention believed to be a nonneoplastic reactive inflammatory condition. Because of its radiographic and histologic similarities to malignancy, IMT can pose a considerable diagnostic dilemma. The purpose of this study is to report the first intramandibular IMT and to discuss the possible nature of this lesion.
Study Design:
Detailed documentation of clinical, radiographic, and histologic features; literature review.
Results:
This lesion showed distinct radiographic, histologic, and immunohistochemical features. The lesion recurred 14 months after initial removal with almost identical histology.
Conclusion:
This is the first documented case of an intramandibular IMT. Due to the rarity of these lesions, their clinical sequelae and prognosis are undetermined. As a result of specific immunohistochemical phenotyping and clinical behavior of this lesion, we favored a diagnosis of inflammatory myofibroblastic tumor. Wide excision with a long-term clinical follow-up is required.
