Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1
Ching-Ting Lin1, Ying-Jung Huang, Pei-Hsuan Chu
1Department of Biological Science and Technology, National Chiao Tung University, 75 Po Ai Street, Hsin Chu 30050, Taiwan, Republic of China.
Research in Microbiology
|September 27, 2005
Abstract:
We herein demonstrate that the hybrid sensor PA1611 carries out specific signal transduction, through HptB (PA3345), to the response regulator PA3346 in Pseudomonas aeruginosa PAO1. As assessed by phenotypic changes in the hptB deletion mutant, the pathway is likely to be involved in the regulation of flagellar activity, the chemotaxis response, twitching motility, and biofilm formation in the bacteria.
