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alpha-Amylases and approaches leading to their enhanced stability
1Department of Biochemical Technology, Slovak Technical University, Bratislava, Czech and Slovak Federal Republic.
FEBS Letters
|June 8, 1992
Abstract:
The recent state of the knowledge of properties and structure of alpha-amylases is reviewed with the aim of elucidation the basis for their stabilization. Three principal ways for obtaining stable alpha-amylases (isolation of enzymes from extremophiles, production of extremophilic enzymes in mesophiles, and modification of mesophilic enzymes) are discussed separately. Detailed experimental examples are given for modification approaches.