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How does fluoride affect dentin microhardness and mineralization?

A Vieira1, R Hancock, M Dumitriu

  • 1Faculty of Dentistry, University of Toronto;

Journal of Dental Research
|September 27, 2005
PubMed
Summary
This summary is machine-generated.

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Long-term fluoride exposure impacts tooth dentin, affecting its hardness and mineralization. Higher fluoride levels and dental fluorosis severity correlate with increased dentin microhardness but not necessarily mineralization.

Area of Science:

  • Dental Science
  • Biomineralization
  • Caries Prevention

Background:

  • Fluoride (F) is crucial for preventing dental caries.
  • Limited data exist on long-term fluoride's effects on dentin mineralization and microhardness.
  • Understanding these effects is vital for optimizing fluoride use in dental health.

Purpose of the Study:

  • To assess how tooth fluoride concentration and dental fluorosis severity influence dentin microhardness and mineralization.
  • To investigate the relationship between environmental (fluoride levels) and genetic (fluorosis) factors and tooth material properties.

Main Methods:

  • Collected 137 teeth from Canada (Montreal, Toronto) and Brazil (Fortaleza) with varying water fluoride levels.
  • Analyzed teeth for dental fluorosis severity, dentin and enamel fluoride concentrations, dentin microhardness, and dentin mineralization.

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Main Results:

  • Dentin fluoride concentration correlated with dental fluorosis severity.
  • Enamel fluoride concentration correlated with dentin microhardness and mineralization.
  • Dental fluorosis severity correlated with dentin microhardness.
  • Teeth from Fortaleza showed higher microhardness and lower mineralization with increased dentin fluoride.
  • Montreal teeth exhibited less severe dental fluorosis compared to Toronto and Fortaleza.

Conclusions:

  • Both genetic factors (dental fluorosis severity) and environmental factors (tooth fluoride concentration) influence dentin microhardness.
  • Environmental factors uniquely impact dentin material properties (mineralization).
  • Geographical location and associated fluoride levels significantly affect dentin characteristics.