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[Prolactinomas and bone mineral density in men].
Erika C O Naliato1, Maria Lucia F Farias, Alice H D Violante
1Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ. erikanaliato@uol.com.br
Arquivos Brasileiros De Endocrinologia E Metabologia
|September 27, 2005
Summary
Hyperprolactinemia, often from prolactinomas, significantly lowers bone mineral density in men. This review examines bone loss prevalence, causes, and treatment impacts in affected males.
Area of Science:
- Endocrinology
- Bone Metabolism
- Reproductive Health
Context:
- Hyperprolactinemia is a common endocrine disorder.
- Prolactinomas are the most frequent cause of hyperprolactinemia.
- Bone mineral density loss is a recognized complication affecting both sexes.
Purpose:
- To analyze bone loss in men with hyperprolactinemia due to prolactinomas.
- To detail the prevalence, clinical relevance, and pathophysiology of bone loss.
- To discuss diagnostic approaches and treatment consequences on bone health.
Summary:
- This paper focuses on male patients with prolactinoma-induced hyperprolactinemia.
- It reviews the pathophysiology linking elevated prolactin to decreased bone mineral density.
- The analysis covers diagnosis and the effects of treating hyperprolactinemia and hypogonadism on bone health.
Impact:
- Highlights the significant impact of hyperprolactinemia on male bone health.
- Provides a comprehensive overview for clinicians managing these patients.
- Informs strategies for preventing and treating bone loss in affected men.