Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital macrodactyly: a clinical study.

Anjum Syed1, Rana Sherwani, Quamar Azam

  • 1Department of Radiodiagnosis, Aligarh Muslim University, Aligarh, India. anjumsyed@yahoo.com

Acta Orthopaedica Belgica
|September 28, 2005
PubMed
Summary

Congenital macrodactyly involves progressive digit enlargement. This study differentiates hand and foot macrodactyly, finding adipose tissue proliferation in feet and nerve involvement in hands as key lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of Apparent Diffusion Coefficient in Differentiating Benign and Malignant Endometrial Pathologies: A Prospective Single-Center Study.

The Indian journal of radiology & imaging·2026
Same author

Occult breast carcinoma presenting as isolated vertebral metastasis with negative PET-CT but detected on contrast-enhanced MRI: A case report.

Radiology case reports·2026
Same author

Influence of inferior glenoid version and glenoid index on recurrent anterior shoulder dislocation.

JSES international·2026
Same author

Artificial Intelligence in Urolithiasis Imaging and Intervention: A Narrative Review of Current Applications, Barriers, and Future Directions.

Cureus·2025
Same author

A Narrative Review of Robotic Aquablation in Benign Prostatic Hyperplasia Care: Where We Are Now.

Cureus·2025
Same author

Variability Between Full-Length Lateral Radiographs and Standard Short Knee Radiographs When Evaluating Posterior Tibial Slope in Revision ACL Patients.

Orthopaedic journal of sports medicine·2025

Area of Science:

  • Medical Science
  • Congenital Malformations
  • Orthopedics

Background:

  • Congenital macrodactyly is a rare condition causing progressive enlargement of digit elements.
  • Understanding the distinct pathologies of hand versus foot macrodactyly is crucial for diagnosis and treatment.

Purpose of the Study:

  • To investigate the similarities and differences between macrodactyly affecting the hand and the foot.
  • To identify the underlying pathological lesion in congenital macrodactyly of the hand and foot.

Main Methods:

  • Analysis of radiographical, operative, and histopathological findings from five congenital macrodactyly cases.
  • Comparative study focusing on differentiating features from other forms of local gigantism.

Main Results:

Related Experiment Videos

  • Macrodactyly of the foot showed excessive fibro-fatty tissue proliferation and large fatty lobules.
  • Digital nerve hypertrophy and tortuosity, common in hand macrodactyly, were absent in foot cases.
  • No associated congenital anomalies, neurofibromatosis stigmata, or chromosomal abnormalities were observed.

Conclusions:

  • The primary lesion in foot macrodactyly is excessive adipose tissue proliferation.
  • Nerve involvement may be the fundamental lesion in hand macrodactyly.
  • Both conditions likely result from local growth factor imbalance, leading to digital overgrowth.