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Moyamoya disease in Washington State and California

Ken Uchino1, S Claiborne Johnston, Kyra J Becker

  • 1Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA. uchinok@upmc.edu

Neurology
|September 28, 2005
PubMed

Insights

Moyamoya disease incidence in California and Washington was 0.086 per 100,000 persons. Asian Americans showed a significantly higher moyamoya disease rate compared to white individuals.

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Moyamoya disease is a rare cerebrovascular disorder.
  • Understanding its epidemiology is crucial for public health planning.

Purpose of the Study:

  • To determine the incidence and demographic patterns of moyamoya disease in California and Washington.
  • To compare incidence rates across different ethnic groups.

Main Methods:

  • Analysis of hospital discharge databases from California and Washington.
  • Inclusion of diagnoses from 1987 to 1998.
  • Calculation of incidence rates and ethnicity-specific rate ratios.

Main Results:

  • A total of 298 moyamoya disease diagnoses were identified.
  • The overall incidence was 0.086 per 100,000 persons.
  • Asian Americans had the highest incidence rate ratio (4.6) compared to whites, followed by African Americans (2.2). Hispanic incidence was lower (0.5).

Conclusions:

  • Moyamoya disease incidence in the studied US regions is lower than in Japan.
  • Significant ethnic disparities in moyamoya disease incidence exist, with Asian Americans disproportionately affected.
  • Further research into the causes of these disparities is warranted.

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