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[Does cranberry juice have bacteriostatic activity?].

Rebeca Monroy-Torres1, Alejandro E Macías

  • 1Facultad de Medicina de la Universidad de Guanajuato. rmonroy79@yahoo.com.mx

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|September 29, 2005
PubMed
Summary
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Cranberry juice does not inhibit bacterial growth in urine or broth, nor does it lower urinary pH. These findings suggest cranberry juice may not be beneficial for preventing urinary tract infections.

Area of Science:

  • Urology
  • Microbiology
  • Nutritional Science

Background:

  • Cranberry juice is commonly used for urinary tract infection (UTI) prevention.
  • The mechanism behind cranberry juice's purported benefits, specifically its effect on bacterial growth and urinary pH, remains unclear.

Purpose of the Study:

  • To investigate the bacteriostatic properties of cranberry juice.
  • To determine if cranberry juice consumption affects urinary pH and inhibits bacterial growth in urine and in vitro.

Main Methods:

  • Urine samples from 20 female students were analyzed before and after cranberry juice consumption.
  • Urine pH and bacterial counts (Escherichia coli) were measured after incubation.
  • In vitro studies assessed E. coli growth in broth with varying cranberry juice concentrations.

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Main Results:

  • Cranberry juice did not demonstrate inhibitory effects on bacterial growth in urine.
  • Urinary pH unexpectedly increased after cranberry juice consumption (p = 0.043).
  • In vitro tests showed no negative trend in E. coli growth with increasing cranberry juice concentrations.

Conclusions:

  • Cranberry juice lacks bacteriostatic properties against E. coli in urine and broth.
  • Ingestion of cranberry juice does not lead to a decrease in urinary pH.
  • The study suggests that the prevention of UTIs by cranberry juice is not attributable to bacteriostatic effects or urinary pH reduction.