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Updated: Aug 15, 2026

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
Published on: December 4, 2016
Occurrence of endocrine-disrupting compounds in reclaimed water from Tianjin, China
Yuqiu Wang1, Wei Hu, Zhonghong Cao
1College of Environmental Science and Engineering, Nankai University, Tianjin 300071, P.R. China. yqwang@nankai.edu.cn
Abstract:
Continuous disposal of endocrine-disrupting compounds (EDCs) into the environment can lead to serious human health problems and can affect plants and aquatic organisms. The determination of EDCs in water has become an increasingly important activity due to our increased knowledge about their toxicities, even at low concentration. The EDCs in water samples from the reclaimed water plant of Tianjin, northern China, were identified by gas chromatography (GC)-mass spectrometry (MS). Important and contrasting EDCs including estrone (E1), 17beta-estradiol (E2), 17alpha-ethynylestradiol (EE2), 4-tert-octylphenol (OP), 4-nonylphenol (NP), bisphenol A (BPA), di-n-butyl phthalate (DnBP), diisobutyl phthalate (DIBP), and di(2-ethylhexyl)phthalate (DEHP) were selected as the target compounds. Concentrations of steroid hormones, alkylphenolic compounds and phthalates ranged from below the limit of detection (LOD) to 8.1 ng L(-1), from
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