Ureteroscopic resection of upper-tract transitional-cell carcinoma

Area of Science:

• Urology
• Oncology
• Surgical Technology

Background:

• Technological advancements are broadening the use of endoscopic procedures for upper-tract transitional-cell carcinoma (TCC).
• Traditional open surgery for TCC may be unsuitable for certain patient groups.
• Nephroureterectomy is the standard for TCC in patients with a healthy contralateral kidney.

Purpose of the Study:

• To review the current applications and role of ureteroscopic management in upper-tract TCC.
• To discuss the expanding indications for endoscopic tumor resection in the upper urinary tract.

Main Methods:

• Literature review of current studies and clinical practices.
• Analysis of treatment outcomes for ureteroscopic tumor resection versus traditional surgery.
• Evaluation of patient selection criteria for endoscopic TCC management.

Main Results:

• Ureteroscopic tumor resection is a feasible option for patients with solitary kidneys, bilateral tumors, renal insufficiency, or comorbidities.
• This endoscopic approach is increasingly considered even for patients with a normal contralateral kidney.
• Technological progress enhances the applicability and safety of these minimally invasive techniques.

Conclusions:

• Ureteroscopic management represents a significant alternative to radical surgery for selected upper-tract TCC cases.
• Endoscopic resection provides a less invasive option, preserving renal function.
• The role of ureteroscopic management in upper-tract TCC is expanding due to improved technology and patient selection.