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Characteristics of hyperthermia and its complications in patients with Prader Willi syndrome
Erdal Ince1, Ergin Ciftçi, Mustafa Tekin
1Division of Pediatric Infectious Disease, Department of Pediatrics, Ankara Univeristy School of Medicine, Dikimevi, Ankara, Turkey. ince@dialup.ankara.edu.tr
Background:
Thermoregulation problems, resulting in hypo- or hyperthermia, have been infrequently reported in children with Prader Willi syndrome (PWS), yet their clinical details remained unknown.
Methods:
The clinical characteristics of three infants with PWS are reported.
Results:
Etiologies of high fever could not be identified in three children with PWS. One of these children was also admitted to the intensive care unit with extremely high body temperature in a life-threatening condition, similar to septic shock, without a plausible explanation.
Conclusion:
Hyperthermia may be a part of the clinical spectrum in young infants with PWS and should be carefully monitored, since it may cause life-threatening complications.
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