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Published on: November 16, 2016
Three cases of vertebral osteomyelitis caused by Streptococcus dysgalactiae subsp. equisimilis
Aravind Kumar1, Jonathan Sandoe1, Naresh Kumar1
1Department of Orthopaedics, Royal Wolverhampton Hospital NHS Trust, Wolverhampton WV10 0QP, UK 2Department of Microbiology, Leeds General Infirmary, Great George's Street, Leeds LS2 9JT, UK.
Abstract:
Three cases of vertebral osteomyelitis caused by Streptococcus dysgalactiae subsp. equisimilis (Strep. equisimilis) are presented here. All three cases presented with fever, back pain, general malaise and weight loss for at least 4 weeks. Diagnosis was established by culture of a spinal biopsy and/or positive blood cultures together with radiological findings. In all three cases, 6-12 weeks of antibiotics were curative without recourse to surgery. The ability of Strep. equisimilis to cause vertebral osteomyelitis is highlighted. The need is emphasized for biopsy and microbiological investigation in patients presenting with back pain, fever, weight loss and evidence of a spinal lesion on imaging, even if neoplastic disease is suspected. Prolonged antibiotic therapy (at least 6 weeks) seems to be indicated.
Insights
Streptococcus dysgalactiae subsp. equisimilis can cause vertebral osteomyelitis. Prompt diagnosis via biopsy and prolonged antibiotic treatment (6-12 weeks) can effectively cure this infection without surgery.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Vertebral osteomyelitis is a serious spinal infection.
- Prompt diagnosis and effective treatment are crucial for patient outcomes.
Observation:
- Three cases of vertebral osteomyelitis caused by Streptococcus dysgalactiae subsp. equisimilis (Strep. equisimilis) are presented.
- Patients exhibited prolonged symptoms including fever, back pain, malaise, and weight loss.
Findings:
- Diagnosis was confirmed through spinal biopsy cultures and/or blood cultures, alongside radiological evidence.
- All three patients were successfully treated with 6-12 weeks of antibiotics, avoiding surgical intervention.
Implications:
- Highlights the potential of Strep. equisimilis to cause vertebral osteomyelitis.
- Emphasizes the importance of biopsy and microbiological investigation for suspected spinal infections, even when malignancy is considered.
- Suggests that prolonged antibiotic therapy (≥6 weeks) is indicated for effective management.
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