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Updated: Aug 15, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
[Ischemic neuroretinopathy associated with use of interferon]
S Miserachs-García1, E Mesa-Toledo, J Arruga-Ginebreda
1Servicio de Oftalmología, Hospital Universitari de Bellvitge, Barcelona, Spain. aquiles77@wanadoo.es
Clinical Case:
A 46-year-old man, treated with peginterferon alpha 2-b and ribavirin for hepatitis C, experienced progressive painless blurring of vision in his left eye over a period of 4 days. Fundoscopy revealed pale temporal segmental edema of the optic disc and retina. Ocular examination and blood tests ruled out other disorders which could explain the visual disturbance.
Discussion:
The patient was diagnosed with an ischemic neuroretinopathy associated with interferon but, due to a favourable visual outcome, the treatment was not discontinued.
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