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Updated: Aug 12, 2026

Manufacture of Concentrated, Lipid-based Oxygen Microbubble Emulsions by High Shear Homogenization and Serial Concentration
Published on: May 26, 2014
[Growth dynamics and the largest size of gas bubbles emerging in body tissues due to decompression]
Abstract:
Symptoms of decompression sickness (DCS) develop when the total volume of gas bubbles due to decompression reaches the magnitude critical for a body tissue. Number of the bubbles is a function of random nucleation intensity before, during or after decompression and tissue superaeration dynamics, whereas their size is unambiguously dependent on a tissue, decompression phase and bubbling time. A mathematical model of bubble tissue dynamics has been proposed for calculating the dynamics of mathematical expectation of the total gas in tissues and mounting a method for comparative analysis of the maximal DCS probability as a result of implementation of different decompression tables. Unequal intensity of nucleation during spaceflight EVA and its ground simulation w/o spacesuit is the course of inequality of decompression safety of these operations.
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